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Among men who had sexual intercourse less than once a week, there were 79 cases of erectile dysfunction per 1,000 men. That number dropped to 32 cases per 1,000 among men who said they had sexual intercourse once a week, and it dropped even further, to 16 per 1,000, among men who said they had sexual intercourse three or more times a week, the researchers reported.
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A comparison of satisfaction rates and ED in subjects treated with sildenafil, intracavernous PGE1 (alprostadil), and penile implant surgery was performed by Rajpurkar and Dhabuwala in 138 men with ED. This was a nonrandomized study in which all subjects were initially offered sildenafil. The mean follow-up was 19.54 months, and questionnaires were used to obtain the data. Their conclusions were that men with a penile implant had significantly better erectile function and satisfaction.
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The most common side effects of sildenafil are headache, flushing and dyspepsia (Table 4).17 A small percentage of patients report an alteration in color perception. Postmarketing reports released by the manufacturer indicate infrequent occurrences of priapism. Because of the presence of phosphodiesterase in the retina, patients with retinitis pigmentosa should not be given sildenafil.
Other causes include diabetes; heart disease; cancer surgery of the prostate, bladder, colon or rectum; high blood pressure medications or antidepressants; a spinal injury; and a hormone imbalance, usually low testosterone, Lipshultz explained.
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Address correspondence to Anthony J. Viera, LT, MC, USNR, Family Practice Department, PSC 490, Box 9097, U.S. Naval Hospital, Guam, FPO AP 96538-1600. Reprints are not available from the authors.
FRIDAY, Sept. 25 (HealthDay News) -- Scientists may have discovered a novel way to treat erectile dysfunction -- using the venom of a deadly spider.
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The PDE11A gene occupies >300 kb of genomic DNA and contains 23 exons of generally small size. The four PDE11A variants have different amino termini due to separate transcriptional start sites (Hetman et al., 2000a; Yuasa et al., 2000). Only PDE11A4 contains two complete GAF domains. Oddly enough, the separate transcriptional start sites for PDE11A1-3 result in production of proteins with incomplete GAF domains (Hetman et al., 2000). PDE11A1 completely lacks the N-terminal-most GAF domain, but contains the complete second GAF domain. PDE11A3 and PDE11A2 have one complete GAF domain and one partial GAF domain. The functional consequence(s) of these truncations is unknown, but the truncations do seem to affect catalytic activity.
In addition to particular disorders, erectile dysfunction may also be a side effect of medications. Medications associated with erectile dysfunction include those used to treat:
The latest Erectile Dysfunction News & Premature Ejaculation News articles published daily. Includes news on erection difficulties, treatment options and causes.
A significant number of men develop impotence from psychological causes that can be overcome. When a physiological cause is treated, subsequent self-esteem problems may continue to impair normal function and performance. Qualified therapists (e.g., sex counselors, psychotherapists) work with couples to reduce tension, improve sexual communication, and create realistic expectations for sex, all of which can improve erectile function.
Anxiety, depression and other emotional issues can lead to premature ejaculation. For these issues, seeking the help of a psychologist, psychiatrist or sex therapist may be helpful. Couples therapy may also help if relationship problems are the cause of premature ejaculation.
An erection starts in the brain, where arousal signals trigger a chemical chain reaction. This process results in relaxation of the muscle in the blood vessel walls that keeps blood from flowing into the penis. Lots of different things can go wrong along the way, which is why there are so many different causes of ED.
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